Hardly ever. If it wasn't that I was in ice skating as a kid, I don't think I would have ever had a reason to travel farther than 50 miles from home before college. I wouldn't call those competition trips vacation though because I didn't feel relaxed at all and didn't really enjoy it that much. We couldn't do anything fun until it was over anyway, and then half the time we went straight home from the rink, so there wasn't any vacation time really.
I have only gone on one two night camping trip over the weekend since HS graduation, and that was no vacation because I left from work, came home on Sunday afternoon totally wiped out and went to work the next morning wishing I hadn't gone camping.