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I actually did know that bark was once made into aspirin. It is probably all synthetic now. Plants being partly safe and partly dangerous is just a quirk of nature. You can eat certain nettles (which look like weeds to me) only at a particular stage in their growth, and only by boiling them to death. If you eat them raw it would be like swallowing insulation, because of the thousands of tiny stinging needles on the plant.